HGH or human growth hormone is an FDA-approved drug used to increase children’s growth rate, with a focus on improving the final height of Turners Syndrome patients. You should think about having HGH Therapy if a Turners Syndrome child is failing to grow or drops below the 5th percentile of the normal female growth curve.
The expected increase in the patient’s height is dependent on a number of factors, including how young the child is when the HGH treatment is started, the dosage prescribed, the duration of the treatment, whether anabolic steroids are used as well, and finally how late estrogen therapy is started. Recently, gains in height of 2 and 6 inches have been reported. However, not every patient will respond to HGH Therapy. The HGH treatment is stopped when the growth experienced is less than 1 inch per year, which is considered ineffective. It is also stopped when the patient reaches a satisfactory height.
Turner Syndrome is not typically life threatening; however, those patients with Turner Syndrome usually require lifelong treatments in order to manage the associated symptoms and illnesses. Most women with Turner syndrome are able to live long, healthy lives.
- Treatment of 80 patients with Turner’s Syndrome with recombinant HGH (YM-17798) for one year at the Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women’s Medical College, Tokyo, Japan. A total of 80 patients with Turner’s Syndrome were treated with methionine-free recombinant HGH for one year. 39 patients were treated with r-hGH at weekly dosage of 0.5 IU/kg and 41 were treated with 1.0 IU/kg/w by daily SC injection. 59% of the patients treated with 0.5 IU/kg/w and 87.8% of the patients treated with 1.0 IU/kg/w showed a growth rate more than 2 cm greater than the pre-treatment values. Theresults indicate that HGH treatment is useful in accelerating growth velocity in patients with Turner’s syndrome.
- Treatment of Turner’s syndrome with recombinant human growth hormone (somatrem) at the Department of Pediatrics, UCLA School of Medicine. This report extends to 3 years the prospective study of the effects of somatrem alone or in combination with oxandrolone on growth in Turner’s Syndrome. 67 patients completed the 1-year study period during which all treatment groups had statistically increased height velocities as compared to the control group. Using bone age determinations and the methods of Bayley and Pinneau, all groups currently show predicted increases in final adult height.
- Behavioral Therapy
Currently, researchers are studying behavioral therapy as a potential treatment for learning difficulties seen in Turner Syndrome patients. There are several different types of behavioral therapy available to help patients to improve communication and social skills. Research suggests that behavioral therapy is more effective when it is started when the patient is 3 years old or younger.
- Recombinant HGH as a Treatment for Turner Syndrome
Many patients with Turner Syndrome receive recombinant HGH therapy to improve their height and ensure there is full sexual development. Patients receive HGH injections a number of times a week. Some research has shown that HGH therapy increases the height of Turner Syndrome girls by an average of three inches during the first year of treatment.
Girls with Turner Syndrome who reach puberty usually need estrogen therapy, which is continued until the girls reach full sexual maturity or until the normal age of menopause. Estrogen therapy has been shown to help patients grow, begin to menstruate, develop normal female sexual characteristics, prevent osteoporosis, and develop proper bone structure.
- Fertility Treatments
In addition to hormonal therapy, some women may want to undergo fertility treatments so they can have children. In vitro fertilization is the most common procedures Turner Syndrome patients undergo.
Prevention Of Turner
There is currently no known method to prevent Turner Syndrome. This disorder is not inherited and it occurs randomly. If a mother has the disorder, it doesn’t mean that her daughter will develop it. If Turner Syndrome is suspected during a pregnancy, there are diagnostic tests that can be performed to determine if the fetus has the disorder. Patients with Turner Syndrome should be in contact with a various medical specialists and are they should undergo routine medical checkups and annual blood tests to check for signs of kidney, heart, thyroid problems or other complications that can develop.