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Can Calorie Restriction Really Reverse Aging?

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What You Need to Know about Calorie Restriction

Calorie restriction is a dietary approach associated with increases in life expectancy through decreasing the total amount of calories eaten every day. Calorie restriction studies has been around over 70 years and current studies have shown a significant increase in lifespan in rats and other animals that underwent a low calorie diet. Calorie restriction is also associated in the prevention and improvement of a number of health conditions, especially those that are associated with cardiovascular diseases and diabetes mellitus.

In calorie restriction, nutritional selections are very essential. Foods that are low in calories but packed with nutrients such as vegetables are much more favored over high carbohydrate and high sugar foods. Anyone who wishes to apply calorie restriction in their diet should have a good knowledge of nutrition and have habitual check-ups with their primary physician. On average, a typical human eats up between 2,000 to 3,000 calories. A person practicing calorie restriction may consume half of that.

In a study on the effects of calorie restriction on rats, scientists found out that decreasing the amount of calories given to rats almost doubled their maximum lifespan. Scientists explained this phenomenon and link the doubling in lifespan to the decrease in cellular division, reduction in metabolism rates, and decrease in the synthesis of free radicals, which have been linked to tissue destruction, made through metabolism. Other organisms that have been used to ascertain the benefits of calorie restriction include monkeys, mice, fruit flies and even yeasts. The findings on some of these animals under calorie restriction found out that not only do they live longer but the way they appear look older when compared to non-treated organisms.

A study of rhesus macaques, which are primates, was started in the year 1989 and is still continuing. The study, so far, has shown that calorie restriction slows down the aging process and essentially slows down the onset of age-related diseases such as cancer, diabetes mellitus, cardiovascular, and neurodegenerative diseases.

Research in female mice has shown that estrogen receptors degenerate as they grow older. Those that were treated with caloric restriction diet during most of their lives sustained higher levels of the said receptors than the non-treated mice. Studies in fungi, particularly in yeast, are easy to manage and many important steps have been done with these particular organisms into understanding the aging.

In human studies, calorie restriction resulted in significantly lower blood pressure, a better condition of the heart, arteries, veins and a lower blood insulin level. As of now, it is uncertain if calorie restriction can really increase the life expectancy in humans.

So much have been learned about the effects of caloric nutrition in different organisms but there are still a lot more that needs to be learned to provide valid, hard proof evidence that calorie restriction, indeed, does contribute to disease prevention and ultimately to live extension.

There is a greater need to replicate these studies done on animals into human test subjects. There are, however, ongoing studies that apply the idea of calorie restriction to human test subjects but so far there is no clear cut evidence of its benefits because of the length of time needed for these studies.

 

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