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| The Daniel Rudman HGH Clinical Experiment |
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What is HGH?
“Human Growth Hormone” (HGH) is produced by the pituitary gland to regulate the
growth of the body. It is used by the body to generate new cells, help the body
regenerate and heal, and make the body grow. It helps the body create healthy
muscles, bones, and other tissues. It also directly works on fatty tissues so
that it is properly metabolized and used for energy. HGH is normally produced by
the body in spurts. It is most active at night when we are sleeping. As we age,
our bodies produce decreasing amounts of HGH.
What is IGF-I?
“Insulin-like Growth Factor – I” or “somatomedin C” aids in the growth of
children and helps in the creation of more complex substances in adults. It is
secreted by the liver and other parts of the body in response to human growth
hormone. This works hand in hand with growth hormone to help bones grow, to
produce protein and other tissues.
What can HGH do for you?
HGH has been proven to help children with growth hormone deficiency, adults who
suffer from declining IGF-I levels, and aid adults who would like to increase
their muscle mass and reduce their fat. What this basically means is HGH mainly
helps with the growth of children, the proper production of muscle, bone, and
other tissues your body needs, and also directly helps you burn fat. Other
effects of HGH include increased systolic blood pressure and increase in plasma
glucose (blood sugar) levels
What are the potential
benefits of HGH?
The potential benefits of HGH are many but let us first focus on the actual
benefits already given by HGH. It helps in diseases where there is a lack of HGH
or IGF-I in children and adults. It also helps your body generate the tissues
and components it needs. It also helps your body burn fat so that it is not
stored in the body. It has the potential to help your body age slower but that
is still yet to be proven by succeeding studies. The physical results can be
compared to physical changes that happen to a 10-20 year old person. HGH may be
used to help prevent muscle loss as a person grows older. Still, more research
is needed to confirm these potential benefits.
What are the risks in
taking HGH treatment?
The main issues with HGH treatment are that the long-term side effects have not
yet been established. In Rudman’s study 12 healthy subjects were administered
HGH for 6 months only. They were tested for physical changes but not for how it
affected them overall. It is not even known if their quality of life has been
affected in a good way. There is also the possibility that it might worsen other
diseases like cancer. One more issue is that it may cause the body to be
dependent on HGH injections. Also misuse of HGH treatment may lead to
manifestations of hypersomatotropism. (Edema, hypertension, diabetes, or
cardiomegaly)
Who were the subjects in
Rudman’s study?
Twelve old men were injected with HGH for a period of 6 months. These subjects
represented a third of the population in the 61 to 81 age bracket. Seven other
men served as the control group where they compared their results. The test has
not taken into account how HGH may affect subjects below 60 years of age.
What did Rudman’s study
prove?
The lack of HGH is one of the factors that contribute to the loss of muscle mass
and the increase of fat mass in the body. By supplementing that lost HGH, lean
muscle mass or muscles increases, fat or adipose mass decreases, your lower back
gets a little stronger, your systolic blood pressure improves (the blood that
goes back to your heart) and that fasting glucose (that means your blood sugar
when you haven’t eaten anything) increases. It doesn’t prove the long term
effects of using HGH. It only confirms that HGH affects these parts of the body.
What are the
implications of Rudman’s study?
Rudman’s study has shown that HGH is a factor that affects the health of men
aged 61 and older. The results were very promising. HGH was shown to be able to change
physical characteristics of its subjects but benefits to overall quality of life
still need to be proved. Does HGH help increase physical strength, and
stamina of its subjects? Are their lives improved by actually taking HGH?
How far have studies on
HGH gone?
So far there have been other studies on HGH that compares its effects on
athletes, women and younger adults. Studies in these areas show that having
additional HGH has no effect on the muscle strength or maximal oxygen uptake. It
also shows that HGH does not give further benefits during exercise. This means
that although HGH has produced a lot of physical changes in the body, the
functions related to these changes have not really improved. More tests have to
be done to clearly show the complete benefits of HGH treatment.
What is next in the
study of HGH and IGF-I?
HGH studies are still in their infant stages. There is yet to be a study of how
the long term supplementation of HGH will affect the human body. A very small
portion of the population has been tested on how HGH would affect them. It is
still not known how increased IGF-I levels will affect people with sicknesses
that are somewhat related to how much IGF-I there is in the body. It is also not
known if the increase in muscle mass, reduction of fat mass, and all the other
effects resulting from the administered HGH have improved the endurance and
stamina of the patients.
What else needs to
be done regarding studies on HGH?
More research needs to be done on the long term effects of HGH and if it is
viable to create a long term HGH treatment for healthy men, and women regardless
of their age. Issues addressing resistance and how other diseases may affect the
supplementation of HGH should also be looked into. Since the study of Rudman
focused on the administering of HGH in only a short period of time, it is not
yet known if the benefits shown in this study could be improved on or maintained
with continued use of HGH. More studies needs to be done before one should even
consider using HGH as a long-term supplement.
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